Generic Imitrex (Sumatriptan) 100mgGeneric Imitrex (Sumatriptan) 100mgGeneric Imitrex (Sumatriptan) 100mg

Generic Imitrex (Sumatriptan) 100mg

Active ingredient:  Sumatriptan

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Imitrex (sumatriptan) is a headache medicine that narrows blood vessels around the brain. Sumatriptan also reduces substances in the body that can trigger headache pain, nausea, sensitivity to light and sound, and other migraine symptoms.

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General information

Imitrex (sumatriptan) is a headache medicine that narrows blood vessels around the brain. Sumatriptan also reduces substances in the body that can trigger headache pain, nausea, sensitivity to light and sound, and other migraine symptoms.

Imitrex tablets are a serotonin 5-HT1 receptor agonist ("triptan"). It works by narrowing blood vessels in the brain, which helps to relieve migraines.

Imitrex is used to treat migraine headaches and cluster headaches in adults. Imitrex will only treat a headache that has already begun. It will not prevent headaches or reduce the number of attacks.

Imitrex should not be used to treat a common tension headache or a headache that causes loss of movement on one side of your body. Use this medicine only if your condition has been confirmed by a doctor as migraine headaches.

Important information

You should not use Imitrex if you have any history of heart disease or coronary artery disease, blood circulation problems, Wolff-Parkinson-White syndrome, uncontrolled high blood pressure, severe liver disease, circulation problems affecting your intestines, history of a stroke, or if your headache seems to be different from your usual migraine headaches.
Do not use Imitrex if you have used an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, tranylcypromine, and others. Do not use Imitrex within 24 hours before or after using any migraine headache medicine.

Directions

Use Imitrex exactly as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label. Overuse of migraine headache medicine can actually make your headaches worse.

Use Imitrex as soon as you notice headache symptoms, or after an attack has already begun.

Your doctor may want to give your first dose of this medicine in a hospital or clinic setting to see if you have any serious side effects.

Take one Imitrex tablet whole with a full glass of water. Do not split the tablet.

After taking a tablet: If your headache does not completely go away, or goes away and comes back, take a second tablet two (2) hours after the first. Do not take more than 200 mg of sumatriptan oral tablets in 24 hours. If your symptoms have not improved, contact your doctor before taking any more tablets.

Precautions

You should not use Imitrex if you are allergic to sumatriptan, or if you have:

  • coronary artery disease, angina (chest pain), blood circulation problems, lack of blood supply to the heart;
  • a heart disorder called Wolff-Parkinson-White syndrome;
  • a history of heart disease, heart attack, or stroke, including "mini-stroke";
  • untreated or or uncontrolled high blood pressure;
  • severe liver disease;
  • circulation problems affecting your intestines; or
  • a headache that seems different from your usual migraine headaches.
  • PREGNANCY and BREAST-FEEDING: It is not known if Imitrex tablets can cause harm to the fetus. If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Imitrex tablets while you are pregnant. Imitrex tablets are found in breast milk. If you are or will be breast-feeding while you use Imitrex tablets, check with your doctor. Discuss any possible risks to your baby.

Do not use Imitrex if you have used an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, tranylcypromine, and others.

To make sure Imitrex is safe for you, tell your doctor if you have:

  • liver or kidney disease;
  • epilepsy or other seizure disorder;
  • high blood pressure, a heart rhythm disorder; or
  • risk factors for coronary artery disease (such as diabetes, menopause, smoking, being overweight, having high cholesterol, having a family history of coronary artery disease, being older than 40 and a man, or being a woman who has had a hysterectomy).
  • Imitrex can affect your pupils during cataract surgery. Tell your eye surgeon ahead of time that you are using this medicine.
  • It is not known whether Imitrex will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medicine. Your name may need to be listed on a sumatriptan pregnancy registry.
  • Sumatriptan can pass into breast milk and may harm a nursing baby. Do not breast-feed within 12 hours after using a sumatriptan. If you use a breast pump during this time, throw out any milk you collect. Do not feed it to your baby.
  • This medicine should not be given to anyone under 18 or over 65 years of age.

Contraindications

Do not use Imitrex within 24 hours before or after using another migraine headache medicine, including:

  • sumatriptan tablets or nasal spray, almotriptan (Axert), eletriptan (Relpax), frovatriptan (Frova), naratriptan (Amerge), rizatriptan (Maxalt), or zolmitriptan (Zomig); or
  • ergot medicine such as dihydroergotamine (D.H.E. 45, Migranal), ergotamine (Ergomar, Cafergot, Migergot), dihydroergotamine (D.H.E. 45, Migranal), or methylergonovine (Methergine).

Imitrex may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert.

Possible side effect

Get emergency medical help if you have signs of an allergic reaction to Imitrex: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Stop using Imitrex and call your doctor if you have:

  • sudden and severe stomach pain and bloody diarrhea;
  • numbness or tingling and a pale or blue-colored appearance in your fingers or toes;
  • seizure (convulsions);
  • dangerously high blood pressure - severe headache, blurred vision, pounding in your neck or ears, nosebleed, anxiety, confusion, severe chest pain, shortness of breath, irregular heartbeats;
  • heart attack symptoms - chest pain or pressure, tightness or pain spreading to your jaw or shoulder, nausea, sweating;
  • signs of a stroke - sudden numbness or weakness (especially on one side of the body), sudden severe headache, slurred speech, problems with vision or balance; or
  • (if you are also taking an antidepressant) - agitation, hallucinations, fever, fast heart rate, overactive reflexes, nausea, vomiting, diarrhea, loss of coordination, fainting.

Common Imitrex side effects may include:

  • numbness or burning sensation;
  • pressure or heavy feeling in any part of your body;
  • dizziness, drowsiness;
  • feeling weak or tired;
  • neck pain or stiffness;
  • flushing (warmth, redness, or tingly feeling); or
  • pain, redness, bleeding, swelling, or bruising where you injected the medicine.

This is not a complete list of side effects and others may occur. 

Drug interaction

Tell your doctor about all medicines you use, and those you start or stop using during your treatment with Imitrex, especially:

  • imatinib, isoniazid, nefazodone;
  • an antibiotic - clarithromycin, erythromycin, telithromycin;
  • an antidepressant - amitriptyline, citalopram, clomipramine, desipramine, doxepin, escitalopram, fluoxetine (Prozac), fluvoxamine, imipramine, nortriptyline, paroxetine, sertraline (Zoloft), trazodone, or vilazodone;
  • antifungal medication - itraconazole, ketoconazole, posaconazole, voriconazole;
  • heart medication - nicardipine, quinidine; or
  • antiviral medicine to treat hepatitis C or HIV/AIDS - boceprevir, atazanavir, cobicistat (Stribild, Tybost), delavirdine, fosamprenavir, indinavir, nelfinavir, ritonavir, saquinavir, telaprevir.

This list is not complete. Other drugs may interact with sumatriptan, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed in this medication guide.

Overdose

Overdose symptoms may include tremors, skin redness, scabs or scaly skin where you injected the medicine, weakness, lack of coordination, breathing problems, blue-colored lips or fingernails, vision problems, seizure (convulsions), or loss of movement in any part of your body.

Storage

Store the medicine at room temperature between 68-77 degrees F (20-25 degrees C) away from light and moisture. Do not store the drugs in the bathroom. Keep all drugs away from reach of children and pets.

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